Regulatory Genomics and Systems Biology

Research on rewiring molecular interactions published in Molecular Cell

Our work on how tissue-specifically spliced segments can rewire protein interactions through disordered segments has been published in Molecular Cell. This work, which has been carried out over the last three years integrates multiple large-scale dataset to arrive at a general principle on how splicing can rewire interactions. The work received coverage in Nature Reviews Genetics and the Gates Trust. The press release on the LMB website can be read here.

Tissue-specific splicing rewires interaction networks

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